Abstract: The conformation and interaction of biologic molecules can be observed directly as a result of the development of nanotechnology. A biomolecule can even be manipulated to obtain a new molecule. Nano-apparati are also used in the diagnosis and therapy of diseases. Nanobiomaterials have good biocompatibility and special nano-effects such as small dimension effects and surface effects. The properties of nanobiomaterials are quite different from those of micron size biomaterials. Nanobiomaterials can be widely used in the fields of monitoring and therapy of cancer, separation of cells or proteins, genic therapy, drug target delivery and release, and so forth.